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Release of Interferon-β (IFN-β) from Probiotic Limosilactobacillus reuteri-IFN-β (LR-IFN-β) Mitigates Gastrointestinal Acute Radiation Syndrome (GI-ARS) following Whole Abdominal Irradiation

SIMPLE SUMMARY: The aim of our study was to assess the efficacy of a novel approach that combines whole abdomen irradiation (WAI) with genetically engineered Limosilactobacillus reuteri, known as Lactobacillus reuteri until recently, releasing interferon-beta (IFN-β; LR-IFN-β). We established that L...

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Detalles Bibliográficos
Autores principales: Hamade, Diala F., Epperly, Michael W., Fisher, Renee, Hou, Wen, Shields, Donna, van Pijkeren, Jan-Peter, Mukherjee, Amitava, Yu, Jian, Leibowitz, Brian J., Vlad, Anda M., Coffman, Lan, Wang, Hong, Huq, M. Saiful, Huang, Ziyu, Rogers, Claude J., Greenberger, Joel S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10046795/
https://www.ncbi.nlm.nih.gov/pubmed/36980556
http://dx.doi.org/10.3390/cancers15061670