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Optimisation Models for Pathway Activity Inference in Cancer

SIMPLE SUMMARY: Subtype classification and prognostic prediction are key research targets in complex diseases such as cancer. In this work, an optimisation model was designed to infer the activity of biological pathways from gene expression values. The optimisation model enables the pathway activity...

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Detalles Bibliográficos
Autores principales: Chen, Yongnan, Liu, Songsong, Papageorgiou, Lazaros G., Theofilatos, Konstantinos, Tsoka, Sophia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10046797/
https://www.ncbi.nlm.nih.gov/pubmed/36980673
http://dx.doi.org/10.3390/cancers15061787