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Caloric Restriction Can Ameliorate Postoperative Cognitive Dysfunction by Upregulating the Expression of Sirt1, MeCP2 and BDNF in the Hippocampal CA1 Region of Aged C57BL/6 Mice

This study aimed to investigate the impact of caloric restriction (CR) on cognitive function in aged C57BL/6 mice after surgery, as well as the underlying mechanisms. Forty 14-month-old male C57BL/6 mice were randomly assigned to the ad libitum (AL, n = 20) group and the CR (n = 20) group. After fee...

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Detalles Bibliográficos
Autores principales: Wei, Lan, Tao, Qiang, Yao, Minmin, Zhao, Zhimeng, Ge, Shengjin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10046819/
https://www.ncbi.nlm.nih.gov/pubmed/36979272
http://dx.doi.org/10.3390/brainsci13030462