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Impact of Translocator Protein 18 kDa (TSPO) Deficiency on Mitochondrial Function and the Inflammatory State of Human C20 Microglia Cells

Microglia are the resident immune cells of the central nervous system. Upon stimulus presentation, microglia polarize from a resting to an activated state. Microglial translocator protein 18 kDa (TSPO) is considered a marker of inflammation. Here, we characterized the role of TSPO by investigating t...

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Detalles Bibliográficos
Autores principales: Bader, Stefanie, Würfel, Thea, Jahner, Tatjana, Nothdurfter, Caroline, Rupprecht, Rainer, Milenkovic, Vladimir M., Wetzel, Christian H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10046935/
https://www.ncbi.nlm.nih.gov/pubmed/36980295
http://dx.doi.org/10.3390/cells12060954