Spike Protein Impairs Mitochondrial Function in Human Cardiomyocytes: Mechanisms Underlying Cardiac Injury in COVID-19

Background: COVID-19 has a major impact on cardiovascular diseases and may lead to myocarditis or cardiac failure. The clove-like spike (S) protein of SARS-CoV-2 facilitates its transmission and pathogenesis. Cardiac mitochondria produce energy for key heart functions. We hypothesized that S1 would...

Descripción completa

Detalles Bibliográficos
Autores principales: Huynh, Tin Van, Rethi, Lekha, Lee, Ting-Wei, Higa, Satoshi, Kao, Yu-Hsun, Chen, Yi-Jen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10046940/
https://www.ncbi.nlm.nih.gov/pubmed/36980218
http://dx.doi.org/10.3390/cells12060877

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10046940/
https://www.ncbi.nlm.nih.gov/pubmed/36980218
http://dx.doi.org/10.3390/cells12060877

Ejemplares similares