Novel Phthalic-Based Anticancer Tyrosine Kinase Inhibitors: Design, Synthesis and Biological Activity

In this work, fragments of isophthalic and terephthalic acids are proposed as a structural scaffold to develop potential inhibitors of protein kinases. Novel isophthalic and terephthalic acid derivatives were designed as type-2 protein kinase inhibitors, synthesized and subjected to physicochemical...

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Detalles Bibliográficos
Autores principales: Kalinichenko, Elena, Faryna, Aliaksandr, Bozhok, Tatyana, Golyakovich, Anna, Panibrat, Alesya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10046946/
https://www.ncbi.nlm.nih.gov/pubmed/36975487
http://dx.doi.org/10.3390/cimb45030117

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10046946/
https://www.ncbi.nlm.nih.gov/pubmed/36975487
http://dx.doi.org/10.3390/cimb45030117

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