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Associations of T-Cell Receptor Repertoire Diversity with L-Asparaginase Allergy in Childhood Acute Lymphoblastic Leukemia

SIMPLE SUMMARY: Asparaginase allergy is the most common side effect of childhood acute lymphoblastic leukemia (ALL) therapy and may affect survival outcomes, but the basis of T-cell responses—especially the T-cell receptor (TCR) repertoire—is unknown. The aim of this study was to characterize the as...

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Detalles Bibliográficos
Autores principales: Lee, Shawn H. R., Li, Zhenhua, Lim, Evelyn H. Z., Chin, Winnie H. N., Jiang, Nan, Chiew, Kean Hui, Chen, Zhiwei, Oh, Bernice L. Z., Tan, Ah Moy, Ariffin, Hany, Yang, Jun J., Yeoh, Allen E. J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10047007/
https://www.ncbi.nlm.nih.gov/pubmed/36980715
http://dx.doi.org/10.3390/cancers15061829