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Epigenetic Modification of Mesenchymal Stromal Cells Derived from Bone Marrow and Embryonal Tumors to Facilitate Immunotherapeutic Approaches in Pediatric Malignancies

Mesenchymal stromal cells (MSC) are part of the bone marrow architecture and contribute to the homeostasis of hematopoietic stem cells. Moreover, they are known to regulate immune effector cells. These properties of MSC are pivotal under physiologic conditions, and they may aberrantly also protect m...

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Detalles Bibliográficos
Autores principales: Kruchen, Anne, Johann, Pascal-David, Rekowski, Laura, Müller, Ingo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10047030/
https://www.ncbi.nlm.nih.gov/pubmed/36975506
http://dx.doi.org/10.3390/cimb45030136