Human Papillomavirus E7 and p16(INK4a) mRNA Multiplexed Quantification by a QuantiGene(TM) Proof-of-Concept Assay Sensitively Detects Infection and Cervical Dysplasia Severity

Background: Persistent infection with human papillomavirus (HPV) can lead to cervical cancer (CxCa). During the progression to CxCa, the expression of HPV oncogenes E6 and E7 is upregulated. In turn, cellular proteins such as p16(INK4a) are also modulated. The combined detection of HPV oncogenes and...

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Detalles Bibliográficos
Autores principales: Skof, Anna Sophie, Rotenberg, Lina, Hannemann, Paul Viktor Felix, Thies, Sarah, Boschetti-Grützmacher, Eleonora, Kaufmann, Andreas M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10047034/
https://www.ncbi.nlm.nih.gov/pubmed/36980443
http://dx.doi.org/10.3390/diagnostics13061135

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10047034/
https://www.ncbi.nlm.nih.gov/pubmed/36980443
http://dx.doi.org/10.3390/diagnostics13061135

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