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Human Papillomavirus E7 and p16(INK4a) mRNA Multiplexed Quantification by a QuantiGene(TM) Proof-of-Concept Assay Sensitively Detects Infection and Cervical Dysplasia Severity
Background: Persistent infection with human papillomavirus (HPV) can lead to cervical cancer (CxCa). During the progression to CxCa, the expression of HPV oncogenes E6 and E7 is upregulated. In turn, cellular proteins such as p16(INK4a) are also modulated. The combined detection of HPV oncogenes and...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
MDPI
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10047034/ https://www.ncbi.nlm.nih.gov/pubmed/36980443 http://dx.doi.org/10.3390/diagnostics13061135 |