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SCD5 Regulation by VHL Affects Cell Proliferation and Lipid Homeostasis in ccRCC

Clear cell renal cell carcinoma (ccRCC) is the most common histological subtype of renal cancer, and inactivation of the VHL tumor suppressor gene is found in almost all cases of hereditary and sporadic ccRCCs. CcRCC is associated with the reprogramming of fatty acid metabolism, and stearoyl-CoA des...

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Detalles Bibliográficos
Autores principales: Ganner, Athina, Philipp, Antonia, Lagies, Simon, Wingendorf, Laura, Wang, Lu, Pilz, Felicitas, Welte, Thomas, Grand, Kelli, Lienkamp, Soeren S., Klein, Marinella, Kammerer, Bernd, Frew, Ian J., Walz, Gerd, Neumann-Haefelin, Elke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10047146/
https://www.ncbi.nlm.nih.gov/pubmed/36980176
http://dx.doi.org/10.3390/cells12060835