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Prevalence of Germline Mutations in Cancer Predisposition Genes in Patients with Pancreatic Cancer or Suspected Related Hereditary Syndromes: Historical Prospective Analysis

SIMPLE SUMMARY: Approximately 5–10% of all pancreatic adenocarcinomas (PDACs) are caused by highly penetrant pathogenic germline variants (PVs). Specific surveillance programs and eventual targeted oncological therapies can be offered to patients carrying some of the known PVs. We prospectively inve...

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Detalles Bibliográficos
Autores principales: Dal Buono, Arianna, Poliani, Laura, Greco, Luana, Bianchi, Paolo, Barile, Monica, Giatti, Valentina, Bonifacio, Cristiana, Carrara, Silvia, Malesci, Alberto, Laghi, Luigi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10047356/
https://www.ncbi.nlm.nih.gov/pubmed/36980738
http://dx.doi.org/10.3390/cancers15061852