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Role of Histone Variant H2A.J in Fine-Tuning Chromatin Organization for the Establishment of Ionizing Radiation-Induced Senescence

Purpose: Radiation-induced senescence is characterized by profound changes in chromatin organization with the formation of Senescence-Associated-Heterochromatin-Foci (SAHF) and DNA-Segments-with-Chromatin-Alterations-Reinforcing-Senescence (DNA-SCARS). Importantly, senescent cells also secrete compl...

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Detalles Bibliográficos
Autores principales: Abd Al-razaq, Mutaz A., Freyter, Benjamin M., Isermann, Anna, Tewary, Gargi, Mangelinck, Adèle, Mann, Carl, Rübe, Claudia E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10047397/
https://www.ncbi.nlm.nih.gov/pubmed/36980257
http://dx.doi.org/10.3390/cells12060916