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Examination of the Functional Relationship between PD-L1 DNA Methylation and mRNA Expression in Non-Small-Cell Lung Cancer

SIMPLE SUMMARY: For non-small-cell lung cancer (NSCLC) patients undergoing immunotherapy blocking the PD-1/PD-L1 interaction, the cancer cell PD-L1 expression level is a determinant of treatment efficiency. This study was conducted to determine whether PD-L1 DNA methylation regulates and can predict...

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Detalles Bibliográficos
Autores principales: Larsen, Trine V., Dybdal, Nina, Daugaard, Tina F., Lade-Keller, Johanne, Lin, Lin, Sorensen, Boe S., Nielsen, Anders L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10047551/
https://www.ncbi.nlm.nih.gov/pubmed/36980795
http://dx.doi.org/10.3390/cancers15061909