Cargando…

Heterogeneity of Cellular Senescence: Cell Type-Specific and Senescence Stimulus-Dependent Epigenetic Alterations

The aim of the present study was to provide a comprehensive characterization of whole genome DNA methylation patterns in replicative and ionizing irradiation- or doxorubicin-induced premature senescence, exhaustively exploring epigenetic modifications in three different human cell types: in somatic...

Descripción completa

Detalles Bibliográficos
Autores principales: Kwiatkowska, Katarzyna Malgorzata, Mavrogonatou, Eleni, Papadopoulou, Adamantia, Sala, Claudia, Calzari, Luciano, Gentilini, Davide, Bacalini, Maria Giulia, Dall’Olio, Daniele, Castellani, Gastone, Ravaioli, Francesco, Franceschi, Claudio, Garagnani, Paolo, Pirazzini, Chiara, Kletsas, Dimitris
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10047656/
https://www.ncbi.nlm.nih.gov/pubmed/36980268
http://dx.doi.org/10.3390/cells12060927