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Prospects of POLD1 in Human Cancers: A Review

SIMPLE SUMMARY: Polymerase delta 1 (POLD1), a catalytic and proofreading subunit of the human DNA polymerase delta (Polδ), plays a vital role in maintaining the stability of the genome. In recent years, POLD1 germline and somatic mutations, as well as gene-expression patterns, have been extensively...

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Detalles Bibliográficos
Autores principales: Gola, Michał, Stefaniak, Przemysław, Godlewski, Janusz, Jereczek-Fossa, Barbara Alicja, Starzyńska, Anna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10047664/
https://www.ncbi.nlm.nih.gov/pubmed/36980791
http://dx.doi.org/10.3390/cancers15061905