Cargando…

Pathogenic Microglia Orchestrate Neurotoxic Properties of Eomes-Expressing Helper T Cells

In addition to disease-associated microglia (DAM), microglia with MHC-II and/or IFN-I signatures may form additional pathogenic subsets that are relevant to neurodegeneration. However, the significance of such MHC-II and IFN-I signatures remains elusive. We demonstrate here that these microglial sub...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhang, Chenyang, Raveney, Ben, Takahashi, Fumio, Yeh, Tzu-wen, Hohjoh, Hirohiko, Yamamura, Takashi, Oki, Shinji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10047905/
https://www.ncbi.nlm.nih.gov/pubmed/36980209
http://dx.doi.org/10.3390/cells12060868