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Emerging Roles of SIRT5 in Metabolism, Cancer, and SARS-CoV-2 Infection

Sirtuin 5 (SIRT5) is a predominantly mitochondrial enzyme catalyzing the removal of glutaryl, succinyl, malonyl, and acetyl groups from lysine residues through a NAD(+)-dependent deacylase mechanism. SIRT5 is an important regulator of cellular homeostasis and modulates the activity of proteins invol...

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Detalles Bibliográficos
Autores principales: Fabbrizi, Emanuele, Fiorentino, Francesco, Carafa, Vincenzo, Altucci, Lucia, Mai, Antonello, Rotili, Dante
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10047932/
https://www.ncbi.nlm.nih.gov/pubmed/36980194
http://dx.doi.org/10.3390/cells12060852