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Emerging Roles of SIRT5 in Metabolism, Cancer, and SARS-CoV-2 Infection
Sirtuin 5 (SIRT5) is a predominantly mitochondrial enzyme catalyzing the removal of glutaryl, succinyl, malonyl, and acetyl groups from lysine residues through a NAD(+)-dependent deacylase mechanism. SIRT5 is an important regulator of cellular homeostasis and modulates the activity of proteins invol...
Autores principales: | Fabbrizi, Emanuele, Fiorentino, Francesco, Carafa, Vincenzo, Altucci, Lucia, Mai, Antonello, Rotili, Dante |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10047932/ https://www.ncbi.nlm.nih.gov/pubmed/36980194 http://dx.doi.org/10.3390/cells12060852 |
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