Development of Tofacitinib Loaded pH-Responsive Chitosan/Mucin Based Hydrogel Microparticles: In-Vitro Characterization and Toxicological Screening

Tofacitinib is an antirheumatic drug characterized by a short half-life and poor permeability, which necessitates the development of sustained release formulation with enhanced permeability potential. To achieve this goal, the free radical polymerization technique was employed to develop mucin/chito...

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Detalles Bibliográficos
Autores principales: Malatani, Rania T., Bilal, Sana, Mahmood, Asif, Sarfraz, Rai Muhammad, Zafar, Nadiah, Ijaz, Hira, Rehman, Umaira, Akbar, Shehla, Alkhalidi, Hala M., Gad, Heba A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10048094/
https://www.ncbi.nlm.nih.gov/pubmed/36975636
http://dx.doi.org/10.3390/gels9030187

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10048094/
https://www.ncbi.nlm.nih.gov/pubmed/36975636
http://dx.doi.org/10.3390/gels9030187

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