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Development of Tofacitinib Loaded pH-Responsive Chitosan/Mucin Based Hydrogel Microparticles: In-Vitro Characterization and Toxicological Screening
Tofacitinib is an antirheumatic drug characterized by a short half-life and poor permeability, which necessitates the development of sustained release formulation with enhanced permeability potential. To achieve this goal, the free radical polymerization technique was employed to develop mucin/chito...
Autores principales: | Malatani, Rania T., Bilal, Sana, Mahmood, Asif, Sarfraz, Rai Muhammad, Zafar, Nadiah, Ijaz, Hira, Rehman, Umaira, Akbar, Shehla, Alkhalidi, Hala M., Gad, Heba A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10048094/ https://www.ncbi.nlm.nih.gov/pubmed/36975636 http://dx.doi.org/10.3390/gels9030187 |
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