Epigenetic Regulation of β-Globin Genes and the Potential to Treat Hemoglobinopathies through Epigenome Editing

Beta-like globin gene expression is developmentally regulated during life by transcription factors, chromatin looping and epigenome modifications of the β-globin locus. Epigenome modifications, such as histone methylation/demethylation and acetylation/deacetylation and DNA methylation, are associate...

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Detalles Bibliográficos
Autores principales: Fontana, Letizia, Alahouzou, Zoe, Miccio, Annarita, Antoniou, Panagiotis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10048329/
https://www.ncbi.nlm.nih.gov/pubmed/36980849
http://dx.doi.org/10.3390/genes14030577

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10048329/
https://www.ncbi.nlm.nih.gov/pubmed/36980849
http://dx.doi.org/10.3390/genes14030577

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