Reduced OPA1, Mitochondrial Fragmentation and Increased Susceptibility to Apoptosis in Granular Corneal Dystrophy Type 2 Corneal Fibroblasts

The progressive degeneration of granular corneal dystrophy type 2 (GCD2) corneal fibroblasts is associated with altered mitochondrial function, but the underlying mechanisms are incompletely understood. We investigated whether an imbalance of mitochondrial dynamics contributes to mitochondrial dysfu...

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Detalles Bibliográficos
Autores principales: Choi, Seung-Il, Lee, Ga-Hyun, Woo, Jong-Hwan, Jun, Ikhyun, Kim, Eung Kweon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10048436/
https://www.ncbi.nlm.nih.gov/pubmed/36980838
http://dx.doi.org/10.3390/genes14030566

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10048436/
https://www.ncbi.nlm.nih.gov/pubmed/36980838
http://dx.doi.org/10.3390/genes14030566

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