Cargando…

EGFRvIII Promotes the Proneural–Mesenchymal Transition of Glioblastoma Multiforme and Reduces Its Sensitivity to Temozolomide by Regulating the NF-κB/ALDH1A3 Axis

(1) Background: Glioblastoma multiforme (GBM) is the most common and malignant intracranial tumor in adults. At present, temozolomide (TMZ) is recognized as the preferred chemotherapeutic drug for GBM, but some patients have low sensitivity to TMZ or chemotherapy resistance to TMZ. Our previous stud...

Descripción completa

Detalles Bibliográficos
Autores principales: Shi, Zhong-Fang, Li, Guan-Zhang, Zhai, You, Pan, Chang-Qing, Wang, Di, Yu, Ming-Chen, Liu, Chi, Zhang, Wei, Yu, Xiao-Guang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10048499/
https://www.ncbi.nlm.nih.gov/pubmed/36980923
http://dx.doi.org/10.3390/genes14030651