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EGFRvIII Promotes the Proneural–Mesenchymal Transition of Glioblastoma Multiforme and Reduces Its Sensitivity to Temozolomide by Regulating the NF-κB/ALDH1A3 Axis
(1) Background: Glioblastoma multiforme (GBM) is the most common and malignant intracranial tumor in adults. At present, temozolomide (TMZ) is recognized as the preferred chemotherapeutic drug for GBM, but some patients have low sensitivity to TMZ or chemotherapy resistance to TMZ. Our previous stud...
Autores principales: | Shi, Zhong-Fang, Li, Guan-Zhang, Zhai, You, Pan, Chang-Qing, Wang, Di, Yu, Ming-Chen, Liu, Chi, Zhang, Wei, Yu, Xiao-Guang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10048499/ https://www.ncbi.nlm.nih.gov/pubmed/36980923 http://dx.doi.org/10.3390/genes14030651 |
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