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Chemical Inhibitors Targeting the Histone Lysine Demethylase Families with Potential for Drug Discovery
The dynamic regulation of histone methylation and demethylation plays an important role in the regulation of gene expression. Aberrant expression of histone lysine demethylases has been implicated in various diseases including intractable cancers, and thus lysine demethylases serve as promising ther...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10048553/ https://www.ncbi.nlm.nih.gov/pubmed/36975603 http://dx.doi.org/10.3390/epigenomes7010007 |