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Chemical Inhibitors Targeting the Histone Lysine Demethylase Families with Potential for Drug Discovery

The dynamic regulation of histone methylation and demethylation plays an important role in the regulation of gene expression. Aberrant expression of histone lysine demethylases has been implicated in various diseases including intractable cancers, and thus lysine demethylases serve as promising ther...

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Detalles Bibliográficos
Autores principales: Das, Nando Dulal, Niwa, Hideaki, Umehara, Takashi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10048553/
https://www.ncbi.nlm.nih.gov/pubmed/36975603
http://dx.doi.org/10.3390/epigenomes7010007