Skin Immuno-CometChip in 3D vs. 2D Cultures to Screen Topical Toxins and Skin-Specific Cytochrome Inducers

The targets of topical genotoxic agents are basal and stem cells of the skin. These cells may misrepair DNA lesions, resulting in deleterious mutations of tumor suppressors or oncogenes. However, the genotoxicity of many compounds has not as yet been determined and needs to be tested using a relevan...

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Detalles Bibliográficos
Autores principales: Rosenthal, Dean S., Kuo, Li-Wei, Seagrave, Sarah L., Soni, Vikas, Islam, Nusrat, Minsky, Geetanjali, Dussan-Cuellar, Lucia, Ell, Brian, Simbulan-Rosenthal, Cynthia M., Sykora, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10048716/
https://www.ncbi.nlm.nih.gov/pubmed/36980902
http://dx.doi.org/10.3390/genes14030630

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10048716/
https://www.ncbi.nlm.nih.gov/pubmed/36980902
http://dx.doi.org/10.3390/genes14030630

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