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Epigenome-Wide Changes in the Cell Layers of the Vein Wall When Exposing the Venous Endothelium to Oscillatory Shear Stress

Epigenomic changes in the venous cells exerted by oscillatory shear stress towards the endothelium may result in consolidation of gene expression alterations upon vein wall remodeling during varicose transformation. We aimed to reveal such epigenome-wide methylation changes. Primary culture cells we...

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Detalles Bibliográficos
Autores principales: Smetanina, Mariya A., Korolenya, Valeria A., Kel, Alexander E., Sevostyanova, Ksenia S., Gavrilov, Konstantin A., Shevela, Andrey I., Filipenko, Maxim L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10048778/
https://www.ncbi.nlm.nih.gov/pubmed/36975604
http://dx.doi.org/10.3390/epigenomes7010008