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CoNiCrMo Particles, but Not TiAlV Particles, Activate the NLRP3 Inflammasome in Periprosthetic Cells

Aseptic loosening is the main reason for arthroplasty failure. The wear particles generated at the tribological bearings are thought to induce an inflammatory tissue response, leading to bone loss and the subsequent loosening of the implant. Different wear particles have been shown to activate the i...

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Detalles Bibliográficos
Autores principales: Brunken, Fenna, Senft, Tristan, Herbster, Maria, Relja, Borna, Bertrand, Jessica, Lohmann, Christoph H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10048784/
https://www.ncbi.nlm.nih.gov/pubmed/36982177
http://dx.doi.org/10.3390/ijms24065108