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Spermidine Rescues Bioenergetic and Mitophagy Deficits Induced by Disease-Associated Tau Protein

Abnormal tau build-up is a hallmark of Alzheimer’s disease (AD) and more than 20 other serious neurodegenerative diseases. Mitochondria are paramount organelles playing a predominant role in cellular bioenergetics, namely by providing the main source of cellular energy via adenosine triphosphate gen...

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Detalles Bibliográficos
Autores principales: Fairley, Lauren H., Lejri, Imane, Grimm, Amandine, Eckert, Anne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10049002/
https://www.ncbi.nlm.nih.gov/pubmed/36982371
http://dx.doi.org/10.3390/ijms24065297