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Inhibitory Effects of Extracellular Vesicles from iPS-Cell-Derived Mesenchymal Stem Cells on the Onset of Sialadenitis in Sjögren’s Syndrome Are Mediated by Immunomodulatory Splenocytes and Improved by Inhibiting miR-125b

Extracellular vesicles (EVs) from allogeneic-tissue-derived mesenchymal stem cells (MSCs) are promising to improve Sjögren’s syndrome (SS) treatment, but their application is hindered by high variations in and limited expandability of tissue MSCs. We derived standardized and scalable MSCs from iPS c...

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Detalles Bibliográficos
Autores principales: Zhao, Qingguo, Bae, Eun-Hye, Zhang, Yu, Shahsavari, Arash, Lotey, Pranayvir, Lee, Ryang Hwa, Liu, Fei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10049013/
https://www.ncbi.nlm.nih.gov/pubmed/36982329
http://dx.doi.org/10.3390/ijms24065258