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Utilization of Supervised Machine Learning to Understand Kinase Inhibitor Toxophore Profiles
There have been more than 70 FDA-approved drugs to target the ATP binding site of kinases, mainly in the field of oncology. These compounds are usually developed to target specific kinases, but in practice, most of these drugs are multi-kinase inhibitors that leverage the conserved nature of the ATP...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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MDPI
2023
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10049021/ https://www.ncbi.nlm.nih.gov/pubmed/36982163 http://dx.doi.org/10.3390/ijms24065088 |