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Senescent Secretome of Blind Mole Rat Spalax Inhibits Malignant Behavior of Human Breast Cancer Cells Triggering Bystander Senescence and Targeting Inflammatory Response

Subterranean blind mole rat, Spalax, has developed strategies to withstand cancer by maintaining genome stability and suppressing the inflammatory response. Spalax cells undergo senescence without the acquisition of senescence-associated secretory phenotype (SASP) in its canonical form, namely, it l...

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Detalles Bibliográficos
Autores principales: Odeh, Amani, Eddini, Hossam, Shawasha, Lujain, Chaban, Anastasia, Avivi, Aaron, Shams, Imad, Manov, Irena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10049022/
https://www.ncbi.nlm.nih.gov/pubmed/36982207
http://dx.doi.org/10.3390/ijms24065132