Metformin reverses oxidative stress-induced mitochondrial dysfunction in pre-osteoblasts via the EGFR/GSK-3β/calcium pathway

Oxidative stress is one of the main causes of osteoblast apoptosis induced by post-menopausal osteoporosis. The authors previously found that metformin can reverse the loss of bone mass in post-menopausal osteoporosis. The present study aimed to further clarify the effects and mechanisms of action o...

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Detalles Bibliográficos
Autores principales: Cao, Fangming, Yang, Keda, Qiu, Shui, Li, Jie, Jiang, Wen, Tao, Lin, Zhu, Yue
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2023
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10049025/
https://www.ncbi.nlm.nih.gov/pubmed/36999607
http://dx.doi.org/10.3892/ijmm.2023.5239

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10049025/
https://www.ncbi.nlm.nih.gov/pubmed/36999607
http://dx.doi.org/10.3892/ijmm.2023.5239

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