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Inhibitors of the NLRP3 inflammasome pathway as promising therapeutic candidates for inflammatory diseases (Review)

The inflammasome regulates innate immunity by serving as a signaling platform. The Nod-like receptor protein 3 (NLRP3) inflammasome, equipped with NLRP3, the adaptor protein apoptosis-associated speck-like protein (ASC) and pro-caspase-1, is by far the most extensively studied and well-characterized...

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Detalles Bibliográficos
Autores principales: Zhang, Xiaolu, Wang, Ziyu, Zheng, Yujia, Yu, Qun, Zeng, Miao, Bai, Liding, Yang, Lin, Guo, Maojuan, Jiang, Xijuan, Gan, Jiali
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10049046/
https://www.ncbi.nlm.nih.gov/pubmed/36960868
http://dx.doi.org/10.3892/ijmm.2023.5238