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Unfolding Individual Domains of BmrA, a Bacterial ABC Transporter Involved in Multidrug Resistance

The folding and stability of proteins are often studied via unfolding (and refolding) a protein with urea. Yet, in the case of membrane integral protein domains, which are shielded by a membrane or a membrane mimetic, urea generally does not induce unfolding. However, the unfolding of α-helical memb...

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Detalles Bibliográficos
Autores principales: Oepen, Kristin, Mater, Veronika, Schneider, Dirk
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10049088/
https://www.ncbi.nlm.nih.gov/pubmed/36982314
http://dx.doi.org/10.3390/ijms24065239