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Neurodegenerative Changes in the Brains of the 5xFAD Alzheimer’s Disease Model Mice Investigated by High-Field and High-Resolution Magnetic Resonance Imaging and Multi-Nuclei Magnetic Resonance Spectroscopy

This study aimed to investigate morphological and metabolic changes in the brains of 5xFAD mice. Structural magnetic resonance imaging (MRI) and (1)H magnetic resonance spectroscopy (MRS) were obtained in 10- and 14-month-old 5xFAD and wild-type (WT) mice, while (31)P MRS scans were acquired in 11-m...

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Detalles Bibliográficos
Autores principales: Yoo, Chi-Hyeon, Kim, Jinho, Baek, Hyeon-Man, Chang, Keun-A, Choe, Bo-Young
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10049146/
https://www.ncbi.nlm.nih.gov/pubmed/36982146
http://dx.doi.org/10.3390/ijms24065073