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Differential Transcriptome Responses in Human THP-1 Macrophages Following Exposure to T98G and LN-18 Human Glioblastoma Secretions: A Simplified Bioinformatics Approach to Understanding Patient-Glioma-Specific Effects on Tumor-Associated Macrophages

A common theme in glioma disease progression is robust infiltration of immune cells within the tumor microenvironment, resulting in a state of chronic inflammation. This disease state is characterized by an abundance of CD68(+) microglia and CD163(+) bone marrow-derived macrophages with the greater...

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Detalles Bibliográficos
Autores principales: Scobie, Micaela R., Abood, Abdullah, Rice, Charles D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10049238/
https://www.ncbi.nlm.nih.gov/pubmed/36982186
http://dx.doi.org/10.3390/ijms24065115