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Hyperbaric Oxygen Therapy Alleviates Paclitaxel-Induced Peripheral Neuropathy Involving Suppressing TLR4-MyD88-NF-κB Signaling Pathway

Paclitaxel (PAC) results in long-term chemotherapy-induced peripheral neuropathy (CIPN). The coexpression of transient receptor potential vanilloid 1 (TRPV1) and Toll-like receptor 4 (TLR4) in the nervous system plays an essential role in mediating CIPN. In this study, we used a TLR4 agonist (lipopo...

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Detalles Bibliográficos
Autores principales: Wang, Shih-Hung, Huang, Shu-Hung, Hsieh, Meng-Chien, Lu, I-Cheng, Chou, Ping-Ruey, Tai, Ming-Hong, Wu, Sheng-Hua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10049379/
https://www.ncbi.nlm.nih.gov/pubmed/36982452
http://dx.doi.org/10.3390/ijms24065379