Novel Synthetic Derivative of Renieramycin T Right-Half Analog Induces Apoptosis and Inhibits Cancer Stem Cells via Targeting the Akt Signal in Lung Cancer Cells

Akt is a key regulatory protein of cancer stem cells (CSCs) and is responsible for cancer aggressiveness and metastasis. Targeting Akt is beneficial for the development of cancer drugs. renieramycin T (RT) has been reported to have Mcl-1 targeting activity, and the study of the structure-activity re...

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Detalles Bibliográficos
Autores principales: Petsri, Korrakod, Yokoya, Masashi, Racha, Satapat, Thongsom, Sunisa, Thepthanee, Chorpaka, Innets, Bhurichaya, Ei, Zin Zin, Hotta, Daiki, Zou, Hongbin, Chanvorachote, Pithi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10049402/
https://www.ncbi.nlm.nih.gov/pubmed/36982418
http://dx.doi.org/10.3390/ijms24065345

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10049402/
https://www.ncbi.nlm.nih.gov/pubmed/36982418
http://dx.doi.org/10.3390/ijms24065345

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