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KIT D816V Mast Cells Derived from Induced Pluripotent Stem Cells Recapitulate Systemic Mastocytosis Transcriptional Profile

Mast cells (MCs) represent a population of hematopoietic cells with a key role in innate and adaptive immunity and are well known for their detrimental role in allergic responses. Yet, MCs occur in low abundance, which hampers their detailed molecular analysis. Here, we capitalized on the potential...

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Detalles Bibliográficos
Autores principales: de Toledo, Marcelo A. S., Fu, Xuhuang, Maié, Tiago, Buhl, Eva M., Götz, Katrin, Schmitz, Susanne, Kaiser, Anne, Boor, Peter, Braunschweig, Till, Chatain, Nicolas, Costa, Ivan G., Brümmendorf, Tim H., Koschmieder, Steffen, Zenke, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10049485/
https://www.ncbi.nlm.nih.gov/pubmed/36982353
http://dx.doi.org/10.3390/ijms24065275