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Hepatocyte-Specific Triggering of Hepatic Stellate Cell Profibrotic Activation by Apoptotic Bodies: The Role of Hepatoma-Derived Growth Factor, HIV, and Ethanol

Liver disease is one of the leading comorbidities in HIV infection. The risk of liver fibrosis development is potentiated by alcohol abuse. In our previous studies, we reported that hepatocytes exposed to HIV and acetaldehyde undergo significant apoptosis, and the engulfment of apoptotic bodies (ABs...

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Detalles Bibliográficos
Autores principales: New-Aaron, Moses, Koganti, Siva Sankar, Ganesan, Murali, Kanika, Sharma, Kumar, Vikas, Wang, Weimin, Makarov, Edward, Kharbanda, Kusum K., Poluektova, Larisa Y., Osna, Natalia A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10049507/
https://www.ncbi.nlm.nih.gov/pubmed/36982417
http://dx.doi.org/10.3390/ijms24065346