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Cathepsin S Knockdown Suppresses Endothelial Inflammation, Angiogenesis, and Complement Protein Activity under Hyperglycemic Conditions In Vitro by Inhibiting NF-κB Signaling

Hyperglycemia plays a key role in the development of microvascular complications, endothelial dysfunction (ED), and inflammation. It has been demonstrated that cathepsin S (CTSS) is activated in hyperglycemia and is involved in inducing the release of inflammatory cytokines. We hypothesized that blo...

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Detalles Bibliográficos
Autores principales: Sayed, Shithima, Faruq, Omar, Preya, Umma Hafsa, Kim, Jee Taek
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10049538/
https://www.ncbi.nlm.nih.gov/pubmed/36982499
http://dx.doi.org/10.3390/ijms24065428