Convenient and Sensitive Measurement of Lactosylceramide Synthase Activity Using Deuterated Glucosylceramide and Mass Spectrometry

Lactosylceramide is necessary for the biosynthesis of almost all classes of glycosphingolipids and plays a relevant role in pathways involved in neuroinflammation. It is synthesized by the action of galactosyltransferases B4GALT5 and B4GALT6, which transfer galactose from UDP-galactose to glucosylce...

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Detalles Bibliográficos
Autores principales: Dei Cas, Michele, Montavoci, Linda, Casati, Sara, Malagolini, Nadia, Dall’Olio, Fabio, Trinchera, Marco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10049619/
https://www.ncbi.nlm.nih.gov/pubmed/36982367
http://dx.doi.org/10.3390/ijms24065291

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10049619/
https://www.ncbi.nlm.nih.gov/pubmed/36982367
http://dx.doi.org/10.3390/ijms24065291

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