Anticancer Small-Molecule Agents Targeting Eukaryotic Elongation Factor 1A: State of the Art

Eukaryotic elongation factor 1A (eEF1A) canonically delivers amino acyl tRNA to the ribosomal A site during the elongation stage of protein biosynthesis. Yet paradoxically, the oncogenic nature of this instrumental protein has long been recognized. Consistently, eEF1A has proven to be targeted by a...

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Detalles Bibliográficos
Autores principales: Zhang, Han, Cai, Jiayou, Yu, Siqi, Sun, Bin, Zhang, Weicheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10049629/
https://www.ncbi.nlm.nih.gov/pubmed/36982256
http://dx.doi.org/10.3390/ijms24065184

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10049629/
https://www.ncbi.nlm.nih.gov/pubmed/36982256
http://dx.doi.org/10.3390/ijms24065184

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