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Microarrays, Enzymatic Assays, and MALDI-MS for Determining Specific Alterations to Mitochondrial Electron Transport Chain Activity, ROS Formation, and Lipid Composition in a Monkey Model of Parkinson’s Disease

Multiple evidences suggest that mitochondrial dysfunction is implicated in the pathogenesis of Parkinson’s disease via the selective cell death of dopaminergic neurons, such as that which occurs after prolonged exposure to the mitochondrial electron transport chain (ETC) complex I inhibitor, 1-methy...

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Detalles Bibliográficos
Autores principales: García-Fernández, María Dolores, Larrea, Ane, Fernández, Roberto, Rodríguez-Puertas, Rafael, Astigarraga, Egoitz, Manuel, Iván, Barreda-Gómez, Gabriel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10049643/
https://www.ncbi.nlm.nih.gov/pubmed/36982541
http://dx.doi.org/10.3390/ijms24065470