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Microarrays, Enzymatic Assays, and MALDI-MS for Determining Specific Alterations to Mitochondrial Electron Transport Chain Activity, ROS Formation, and Lipid Composition in a Monkey Model of Parkinson’s Disease
Multiple evidences suggest that mitochondrial dysfunction is implicated in the pathogenesis of Parkinson’s disease via the selective cell death of dopaminergic neurons, such as that which occurs after prolonged exposure to the mitochondrial electron transport chain (ETC) complex I inhibitor, 1-methy...
Autores principales: | García-Fernández, María Dolores, Larrea, Ane, Fernández, Roberto, Rodríguez-Puertas, Rafael, Astigarraga, Egoitz, Manuel, Iván, Barreda-Gómez, Gabriel |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10049643/ https://www.ncbi.nlm.nih.gov/pubmed/36982541 http://dx.doi.org/10.3390/ijms24065470 |
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