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KDM5D Histone Demethylase Identifies Platinum-Tolerant Head and Neck Cancer Cells Vulnerable to Mitotic Catastrophe

Head and neck squamous cell carcinoma (HNSCC) is a major contributor to cancer incidence globally and is currently managed by surgical resection followed by adjuvant chemoradiotherapy. However, local recurrence is the major cause of mortality, indicating the emergence of drug-tolerant persister cell...

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Detalles Bibliográficos
Autores principales: Chen, Tsung-Ming, Huang, Chih-Ming, Setiawan, Syahru Agung, Hsieh, Ming-Shou, Sheen, Chih-Chi, Yeh, Chi-Tai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10049674/
https://www.ncbi.nlm.nih.gov/pubmed/36982384
http://dx.doi.org/10.3390/ijms24065310