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Reconstructing Clonal Evolution—A Systematic Evaluation of Current Bioinformatics Approaches

The accurate reconstruction of clonal evolution, including the identification of newly developing, highly aggressive subclones, is essential for the application of precision medicine in cancer treatment. Reconstruction, aiming for correct variant clustering and clonal evolution tree reconstruction,...

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Detalles Bibliográficos
Autores principales: Sandmann, Sarah, Richter, Silja, Jiang, Xiaoyi, Varghese, Julian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10049679/
https://www.ncbi.nlm.nih.gov/pubmed/36982036
http://dx.doi.org/10.3390/ijerph20065128