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Diet Control and Swimming Exercise Ameliorate HFD-Induced Cognitive Impairment Related to the SIRT1-NF-κB/PGC-1α Pathways in ApoE-/- Mice

High-fat diet- (HFD-) induced neuroinflammation may ultimately lead to an increased risk of cognitive impairment. Here, we evaluate the effects of diet control and swimming or both on the prevention of cognitive impairment by enhancing SIRT1 activity. Twenty-week-old ApoE-/- mice were fed a HFD for...

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Detalles Bibliográficos
Autores principales: Wei, Wei, Lin, Zhicheng, Xu, PeiTao, Lv, Xinru, Lin, Libin, Li, Yongxu, Zhou, Yangjie, Lu, Taotao, Xue, Xiehua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10049848/
https://www.ncbi.nlm.nih.gov/pubmed/36999158
http://dx.doi.org/10.1155/2023/9206875